HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24145035
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 303
+	Hs
		232980 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		232821 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		1130729 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Dm
		1364726 SUR8_DROME (638-866): 3.65e-36: 149: 21.30		Q9VH81_DROME (4-246): 6.54e-32: 125: 16.87
+	Hs
		1130585 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		297066 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Hs
		858664 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91