HitPredict

Interactor 1: CCNT1 (O60563)
Cyclin-T1 (CycT1) (Cyclin-T)
Gene: CCNT1

Interactor 2: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 795
+	Hs
		236679 CCNT1_HUMAN (1-715): 0: 591: 100.00		CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84
+	Hs
		236764 CCNT1_HUMAN (1-715): 0: 591: 100.00		CDK10_HUMAN (429-760): 3.17e-133: 401: 52.41
+	Hs
		237380 CCNT2_HUMAN (3-673): 1.04e-114: 364: 44.40		CD11B_HUMAN (1-795): 0: 574: 100.00
+	Hs
		596833 CCNL1_HUMAN (9-523): 6.46e-79: 264: 17.89		CD11B_HUMAN (1-795): 0: 574: 100.00
+	Hs
		1356304 CCNL1_HUMAN (9-523): 6.46e-79: 264: 17.89		CD11A_HUMAN (1-795): 0: 561: 96.86
+	Hs
		625350 CCNA1_HUMAN (4-273): 9.89e-86: 280: 16.24		CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96
+	At
		1210030 CCT14_ARATH (4-532): 4.44e-95: 307: 23.09		CDKC2_ARATH (425-792): 5.28e-136: 414: 40.73
+	At
		1210031 CCT14_ARATH (4-532): 4.44e-95: 307: 23.09		CDKC1_ARATH (424-789): 2.98e-136: 414: 41.73
+	At
		1259119 CCT15_ARATH (4-531): 3.76e-93: 303: 23.42		CDKC2_ARATH (425-792): 5.28e-136: 414: 40.73
+	At
		1323943 CCT15_ARATH (4-531): 3.76e-93: 303: 23.42		CDKC1_ARATH (424-789): 2.98e-136: 414: 41.73
+	Mm
		956329 CCNA1_MOUSE (4-274): 4.65e-86: 279: 16.54		CDK2_MOUSE (435-731): 8.4e-145: 431: 38.15
+	At
		1247203 CCL11_ARATH (6-408): 2.47e-76: 253: 20.95		Q9CAG1_ARATH (34-774): 6.12e-144: 443: 34.57
+	Hs
		414855 CCNA1_HUMAN (4-273): 9.89e-86: 280: 16.24		CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84
+	At
		1247204 CCL11_ARATH (6-408): 2.47e-76: 253: 20.95		CDKG1_ARATH (171-742): 7.21e-139: 425: 37.33
+	At
		621697 CCA31_ARATH (1-274): 9.12e-80: 260: 13.17		CDKA1_ARATH (435-726): 1.55e-138: 412: 45.09
+	At
		621661 CCB12_ARATH (4-273): 6.27e-77: 256: 13.33		CDKA1_ARATH (435-726): 1.55e-138: 412: 45.09
+	Dm
		618404 Q961D1_DROME (9-334): 1.69e-76: 253: 25.52		CDK1_DROME (435-727): 4.62e-137: 409: 42.37
+	Dm
		618463 Q961D1_DROME (9-334): 1.69e-76: 253: 25.52		CDK2_DROME (435-749): 1.01e-128: 388: 43.49
+	Hs
		841352 CCNL1_HUMAN (9-523): 6.46e-79: 264: 17.89		CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69
+	At
		1106926 CCB13_ARATH (4-278): 7.09e-79: 260: 14.91		CDKD2_ARATH (446-756): 1.42e-72: 242: 40.25