HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19407811
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 685
+	Hs
		210979 BUB1_HUMAN (53-1042): 1.59e-170: 531: 19.04		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475314 KPCA_HUMAN (576-1044): 3.3e-109: 356: 13.75		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475390 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475723 KCC2D_HUMAN (764-1021): 2.99e-96: 316: 16.61		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		1091641 KIN10_ARATH (765-1047): 8.11e-109: 350: 15.15		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		681773 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		474936 AKT2_HUMAN (629-1044): 6.22e-114: 362: 12.59		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		474935 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Rn
		514950 KCC2G_RAT (764-985): 3.61e-63: 225: 19.05		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		550163 KCC2D_RAT (753-985): 5.7e-62: 222: 17.36		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		506748 KCC2A_RAT (764-985): 1.69e-60: 216: 17.75		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		160345 AURKA_HUMAN (671-986): 1.25e-38: 151: 16.01		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70