HitPredict

Interactor 1: IF4E2 (O60573)
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3)
Gene: EIF4E2

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 15161933
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 245
+	Hs
		237193 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		237167 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		237173 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		237191 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		237203 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49