Interactor 1: SPT5H (O55201)
Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit)
Gene: Supt5h
Interactor 2: SPT4A (P63271)
Transcription elongation factor SPT4-A (DRB sensitivity-inducing factor small subunit 1) (DSIF small subunit 1) (Transcription elongation factor SPT4 1)
Gene: Supt4h1a
Species: Mus musculus
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20211142 |
| Identification Methods | two hybrid, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | KOW~Spt4, Spt4~Spt5-NGN |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0032044 - DSIF complex GO:0046982 - protein heterodimerization activity GO:0140673 - transcription elongation-coupled chromatin remodeling |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
