HitPredict

Interactor 1: IF4E2 (O60573)
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3)
Gene: EIF4E2

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 522
+	Hs
		417049 IF4E_HUMAN (32-233): 2.86e-91: 269: 31.40		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		237159 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		416927 IF4E_HUMAN (32-233): 2.86e-91: 269: 31.40		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		417008 IF4E_HUMAN (32-233): 2.86e-91: 269: 31.40		TRI22_HUMAN (56-361): 5.96e-39: 150: 15.51