HitPredict

Interactor 1: ILK (O55222)
Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK)
Gene: ILK

Interactor 2: CHIP (Q9WUD1)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: Stub1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	28546219, 23612611
Identification Methods	affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 452 Mm			1 304
+	Hs
		1104535 ILK_HUMAN (1-452): 7.38e-143: 417: 99.56		CHIP_HUMAN (1-304): 7.94e-68: 215: 97.04
+	Hs
		1104484 ILK_HUMAN (1-452): 7.38e-143: 417: 99.56		UN45A_HUMAN (13-215): 7.78e-34: 132: 21.70
+	Hs
		916652 ILK_HUMAN (1-452): 7.38e-143: 417: 99.56		PPP5_HUMAN (2-201): 2.85e-32: 126: 18.18
+	Hs
		557526 SRC_HUMAN (173-448): 2.05e-103: 319: 24.56		CHIP_HUMAN (1-304): 7.94e-68: 215: 97.04
+	Hs
		185661 ILK_HUMAN (1-452): 7.38e-143: 417: 99.56		OGT1_HUMAN (21-235): 1.03e-14: 76.6: 10.70
+	Hs
		731259 ILK_HUMAN (1-452): 7.38e-143: 417: 99.56		STIP1_HUMAN (3-264): 1.27e-12: 70: 9.49
+	Hs
		185363 YES_HUMAN (176-448): 9.89e-103: 318: 26.60		OGT1_HUMAN (21-235): 1.03e-14: 76.6: 10.70
+	Mm
		1283438 M3K20_MOUSE (188-451): 3.57e-26: 114: 27.99		WDTC1_MOUSE (25-140): 3.29e-09: 59.7: 31.50