HitPredict

Interactor 1: PP2BB (P16298)
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta)
Gene: PPP3CB

Interactor 2: PP2BC (P48454)
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)
Gene: PPP3CC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos
Common GO terms GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005955 - calcineurin complex
GO:0006470 - protein dephosphorylation
and 9 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 524
Hs

1 512
+ Hs
+ Dm
+ Hs
+ Mm
+ Sc
+ Sc
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024