HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding GO:0016020 - membrane and 1 others more... GO:0043657 - host cell
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Hs			1 1475
+	Hs
		134853 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		168626 IMA6_HUMAN (1-536): 3.72e-149: 440: 83.67		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		131403 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		834566 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		134854 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		131404 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		834694 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		134921 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		RGPD4_HUMAN (1136-1440): 1.07e-38: 160: 16.39
+	Hs
		63862 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		RGPD3_HUMAN (1136-1440): 4.22e-38: 158: 16.39
+	Sp
		293244 IMA2_SCHPO (11-536): 4.57e-144: 427: 52.26		NU124_SCHPO (702-1470): 4.84e-40: 164: 11.67
+	Hs
		238746 IMA7_HUMAN (1-536): 7e-160: 467: 100.00		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		131388 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		238723 IMA7_HUMAN (1-536): 7e-160: 467: 100.00		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Hs
		134976 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		65034 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		P121C_HUMAN (211-1269): 1.45e-20: 101: 9.16
+	Hs
		131525 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		853745 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		65033 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		P121C_HUMAN (211-1269): 1.45e-20: 101: 9.16
+	Hs
		134948 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Hs
		131490 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24