HitPredict

Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0042803 - protein homodimerization activity GO:0045296 - cadherin binding GO:0046982 - protein heterodimerization activity
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 243
+	Hs
		240449 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30
+	Hs
		310881 SNX5_HUMAN (123-517): 2.28e-68: 227: 22.89		VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00
+	Hs
		310865 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00