HitPredict

Interactor 1: DPM1 (O60762)
Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1)
Gene: DPM1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 1374
+	Hs
		240523 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		240588 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54
+	Hs
		240513 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		240514 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		ROS1_HUMAN (131-392): 2.54e-37: 156: 34.91
+	Hs
		240591 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		240509 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		240654 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		ALK_HUMAN (109-386): 2.69e-32: 139: 32.99