HitPredict

Interactor 1: TOM1 (O60784)
Target of Myb1 membrane trafficking protein (Target of Myb protein 1)
Gene: TOM1

Interactor 2: Q6FIE9 (Q6FIE9)
TOLLIP protein (Toll interacting protein) (cDNA, FLJ96670, Homo sapiens toll interacting protein (TOLLIP), mRNA)
Gene: TOLLIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043130 - ubiquitin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 274
+	Hs
		241195 TOM1_HUMAN (1-492): 5.19e-178: 510: 100.00		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Mm
		292211 TOM1_MOUSE (1-492): 6e-180: 515: 89.43		TOLIP_MOUSE (1-273): 2.66e-165: 460: 93.04
+	Rn
		58593 Q5XI21_RAT (1-492): 1.46e-178: 511: 88.82		TOLIP_RAT (1-273): 9.9e-166: 461: 93.41
+	Hs
		1173027 TM1L2_HUMAN (1-492): 2.32e-147: 432: 61.45		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		272820 TM1L1_HUMAN (7-487): 1.65e-105: 324: 29.66		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1270615 STAM1_HUMAN (1-477): 6.09e-92: 291: 19.27		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1327604 GGA1_HUMAN (12-450): 6.7e-91: 291: 21.37		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1327603 GGA2_HUMAN (5-456): 4.77e-89: 286: 19.01		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		1327594 GGA3_HUMAN (12-476): 3.9e-84: 276: 21.28		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00
+	Hs
		160182 HGS_HUMAN (10-465): 5.12e-76: 255: 17.90		TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00