HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: PAK4 (O96013)
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Gene: PAK4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29100370
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 591
+	Sc
		355992 H2B2_YEAST (3-125): 7.25e-37: 123: 70.73		STE20_YEAST (11-591): 6.96e-143: 439: 31.62
+	Sc
		355616 H2B1_YEAST (3-125): 3e-36: 122: 70.73		STE20_YEAST (11-591): 6.96e-143: 439: 31.62
+	Hs
		617927 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94
+	Hs
		420807 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94
+	Hs
		682181 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94
+	Hs
		682137 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94
+	Hs
		682194 H2B3B_HUMAN (1-126): 8.48e-52: 161: 94.44		AKT2_HUMAN (261-583): 1.6e-127: 384: 22.94
+	Hs
		1023051 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		STK4_HUMAN (298-588): 1.44e-122: 372: 35.50
+	Hs
		617936 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27
+	Hs
		420815 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27
+	Hs
		850663 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27
+	Hs
		707559 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27
+	Hs
		241401 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		PAK3_HUMAN (3-210): 5.28e-25: 111: 19.56
+	Hs
		277601 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PAK3_HUMAN (3-210): 5.28e-25: 111: 19.56