HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: LHX4 (Q969G2)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.600

Property	Details
Experiments	25416956, 25910212
Identification Methods	two hybrid, mammalian protein protein interaction trap, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid bait and prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 390
+	Hs
		243160 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		LHX3_HUMAN (1-390): 1.94e-87: 271: 60.25
+	Hs
		924721 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		LMX1A_HUMAN (2-347): 2.28e-68: 222: 27.90
+	Hs
		150505 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		ABLM1_HUMAN (29-193): 3.59e-24: 106: 24.26
+	Hs
		150552 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		ABLM1_HUMAN (29-193): 3.59e-24: 106: 24.26
+	Hs
		300996 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		ABLM3_HUMAN (30-193): 1.92e-23: 104: 21.77
+	Hs
		150489 SH21B_HUMAN (5-119): 1.69e-34: 117: 42.61		ABLM1_HUMAN (29-193): 3.59e-24: 106: 24.26
+	Hs
		412099 FYN_HUMAN (1-125): 4.91e-37: 133: 18.52		LIMK1_HUMAN (4-84): 2.69e-09: 60.7: 15.48