HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: ELK4 (P28324)
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)
Gene: ELK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 431
+	Hs
		657838 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657854 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.03		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657814 H2BFS_HUMAN (1-126): 9.81e-54: 166: 98.41		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657821 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657848 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657852 H2B1N_HUMAN (1-126): 2.97e-53: 165: 98.41		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657815 H2B1D_HUMAN (1-126): 3.17e-53: 164: 98.41		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657855 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		657849 H2B1A_HUMAN (1-126): 3.03e-46: 147: 83.47		ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00
+	Hs
		918387 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		ELF2_HUMAN (4-362): 3.65e-33: 133: 18.96
+	Hs
		918286 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		ELF3_HUMAN (5-89): 3.36e-32: 127: 42.53
+	Hs
		692119 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		ELF1_HUMAN (4-381): 8.23e-28: 117: 19.31