HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 491
+	Hs
		420827 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		918295 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		962807 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		962859 H2B3B_HUMAN (1-126): 8.48e-52: 161: 94.44		MDM2_HUMAN (1-491): 0: 710: 100.00