HitPredict

Interactor 1: CCD22 (O60826)
Coiled-coil domain-containing protein 22
Gene: CCDC22

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 627 Hs			1 1193
+	Hs
		528435 MYH4_HUMAN (180-627): 1.26e-10: 66.9: 11.18		MYH8_HUMAN (287-953): 3.4e-31: 135: 11.77
+	Hs
		502933 MYH4_HUMAN (180-627): 1.26e-10: 66.9: 11.18		MYH3_HUMAN (173-1134): 9.39e-30: 131: 11.22
+	Hs
		528432 MYH8_HUMAN (174-626): 3.14e-09: 62.3: 12.74		MYH13_HUMAN (163-961): 2.75e-24: 113: 9.10
+	Hs
		522657 MYH4_HUMAN (180-627): 1.26e-10: 66.9: 11.18		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91
+	Hs
		1200984 LUZP1_HUMAN (294-623): 8.42e-15: 80.4: 15.95		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		1268126 MRCKB_HUMAN (183-549): 2.25e-13: 75.8: 11.85		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		1078856 ITSN1_HUMAN (305-627): 2.04e-15: 82.3: 12.07		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		254476 ROCK2_HUMAN (177-622): 3.7e-10: 65.4: 12.90		ROCK1_HUMAN (546-1186): 1.44e-17: 90.8: 14.97
+	Hs
		1068587 LUZP1_HUMAN (294-623): 8.42e-15: 80.4: 15.95		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Rn
		92843 CTRO_RAT (239-626): 2.18e-11: 69.6: 13.73		ROCK2_RAT (674-1191): 5.21e-15: 82.7: 11.69
+	Hs
		724905 LUZP1_HUMAN (294-623): 8.42e-15: 80.4: 15.95		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		1068551 FIL1L_HUMAN (265-623): 1.97e-13: 75.8: 15.87		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		149008 LUZP1_HUMAN (294-623): 8.42e-15: 80.4: 15.95		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Bt
		1100183 ROCK2_BOVIN (200-622): 2.41e-09: 62.7: 12.69		ROCK2_BOVIN (713-1193): 4.55e-15: 82.7: 12.55
+	Hs
		725097 MYH11_HUMAN (173-627): 1.56e-10: 66.5: 10.20		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		148466 MYH11_HUMAN (173-627): 1.56e-10: 66.5: 10.20		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		502901 MYH3_HUMAN (173-624): 3.16e-10: 65.8: 10.02		MYH6_HUMAN (958-1190): 3.59e-09: 63.7: 14.16