HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: A16A1 (Q8IZ83)
Aldehyde dehydrogenase family 16 member A1
Gene: ALDH16A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 802
+	Hs
		240477 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ALDH2_HUMAN (500-802): 9.8e-114: 357: 25.64
+	Hs
		240857 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		AL1B1_HUMAN (496-802): 2.21e-112: 353: 28.39
+	Hs
		240333 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		AL1A2_HUMAN (508-802): 1.07e-110: 349: 25.89
+	Hs
		241059 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		AL9A1_HUMAN (531-802): 5.17e-98: 315: 24.55
+	Hs
		242896 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		AL8A1_HUMAN (528-802): 7.79e-94: 304: 24.73
+	Sc
		509626 UBI4P_YEAST (1-229): 3.44e-60: 203: 18.72		ALDH2_YEAST (518-802): 2.63e-101: 324: 24.92
+	At
		1168332 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		AL2B4_ARATH (508-802): 1.19e-109: 347: 27.72
+	At
		1167648 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		AL2C4_ARATH (521-802): 2.02e-99: 319: 25.17