HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: ATF3 (P18847)
Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3)
Gene: ATF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.542

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 181
+	Hs
		337295 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25
+	Hs
		337306 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73
+	Mm
		337616 ABL1_MOUSE (1-127): 5.17e-40: 143: 26.72		JUN_MOUSE (10-155): 1.94e-23: 96.5: 19.46
+	Hs
		337332 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		FOSL1_HUMAN (42-169): 1.11e-22: 93.4: 26.76
+	Hs
		243117 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25
+	Hs
		401572 CSK_HUMAN (1-126): 1.42e-34: 125: 25.40		JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73
+	Hs
		155823 SH21B_HUMAN (5-119): 1.69e-34: 117: 42.61		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25