HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NSD2 (O96028)
Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein)
Gene: NSD2

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.953

The method score is based on:

Property Details
Experiments 31248990, 31753913, 31239290, 32416067, 30554943, 21555454, 27291650
Identification Methods proximity labelling technology, affinity chromatography technology, nuclear magnetic resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~PHD
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1362
Hs

1 1365
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024