HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31239290, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0010971 - positive regulation of G2/M transition of mitotic cell cycle GO:0019899 - enzyme binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 639
+	Hs
		243843 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		243887 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Sc
		450167 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		HSP73_YEAST (7-639): 0: 915: 72.22
+	Sc
		450006 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		HSP73_YEAST (7-639): 0: 915: 72.22