HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31239290, 32416067, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 699
+	Hs
		244311 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		243848 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		244571 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		244652 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		631406 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		973337 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		631428 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		1060988 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		508826 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		509005 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Mm
		964613 PB1_MOUSE (9-629): 2.51e-37: 156: 12.50		TOP2A_MOUSE (6-368): 7.3e-51: 194: 16.17
+	Hs
		1061027 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		631500 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		1067006 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		1067043 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		509044 PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		1123378 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Dm
		113976 M9PB30_DROME (168-975): 2.55e-17: 90.9: 12.03		M9PB30_DROME (8-449): 3.6e-13: 75.8: 8.89