HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 34709266
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0019899 - enzyme binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 485
+	Hs
		244870 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		244386 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		243726 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		1262836 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		631565 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1067114 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		243699 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		245142 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		1262828 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		631421 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		1031863 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		1017343 BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1262830 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		RERE_HUMAN (74-483): 7.34e-66: 232: 14.51
+	Hs
		1017290 BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		296001 BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		319398 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		1262850 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11