HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 1299
+	Hs
		247241 PHLP1_HUMAN (1-1717): 0: 1481: 100.00		MYH9_HUMAN (450-1298): 2.53e-22: 106: 10.29
+	Hs
		247452 PHLP1_HUMAN (1-1717): 0: 1481: 100.00		RRBP1_HUMAN (256-1295): 3.17e-16: 86.7: 9.18
+	Hs
		247335 PHLP1_HUMAN (1-1717): 0: 1481: 100.00		PLEC_HUMAN (141-969): 1.17e-15: 85.2: 10.37
+	Hs
		247225 PHLP1_HUMAN (1-1717): 0: 1481: 100.00		DESP_HUMAN (612-1126): 9.08e-13: 75.5: 14.07
+	Hs
		247426 PHLP1_HUMAN (1-1717): 0: 1481: 100.00		SLK_HUMAN (753-1031): 1.31e-09: 65: 17.39
+	Hs
		116704 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		I1E4Y6_HUMAN (1-1299): 6.57e-105: 364: 98.26
+	Hs
		70026 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		A8MQ02_HUMAN (301-880): 1.53e-51: 202: 15.84
+	Hs
		936420 ERBIN_HUMAN (637-806): 2.74e-09: 64.3: 26.86		AFAD_HUMAN (301-880): 7.81e-53: 206: 16.87
+	Hs
		1209326 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		KI21A_HUMAN (684-1261): 3.15e-30: 132: 13.71
+	Hs
		773198 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		MYH10_HUMAN (705-1295): 1.39e-22: 107: 7.71
+	Hs
		772841 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		MYH9_HUMAN (450-1298): 2.53e-22: 106: 10.29
+	Hs
		1143147 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		PLEC_HUMAN (141-969): 1.17e-15: 85.2: 10.37
+	Hs
		587688 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		DESP_HUMAN (612-1126): 9.08e-13: 75.5: 14.07
+	Hs
		1209782 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		MYH2_HUMAN (180-850): 1.3e-10: 68.6: 10.50
+	Hs
		1209322 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		MYH14_HUMAN (719-1022): 6.77e-10: 66.2: 19.94
+	Hs
		1209644 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		SLK_HUMAN (753-1031): 1.31e-09: 65: 17.39
+	Hs
		67393 LRRK2_HUMAN (716-1019): 5.98e-18: 93.2: 29.32		A7BI36_HUMAN (399-1298): 2.07e-09: 64.4: 7.43