HitPredict

Interactor 1: ACSL4 (O60488)
Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4)
Gene: ACSL4

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 711 Hs			1 196
+	Hs
		249451 ACSL4_HUMAN (1-711): 0: 756: 100.00		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		249449 ACSL4_HUMAN (1-711): 0: 756: 100.00		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		339473 ACSL3_HUMAN (1-711): 0: 720: 65.54		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		339465 ACSL3_HUMAN (1-711): 0: 720: 65.54		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		339417 ACSL3_HUMAN (1-711): 0: 720: 65.54		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		339477 ACSL3_HUMAN (1-711): 0: 720: 65.54		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		339404 ACSL3_HUMAN (1-711): 0: 720: 65.54		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		339461 ACSL3_HUMAN (1-711): 0: 720: 65.54		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Hs
		339462 ACSL3_HUMAN (1-711): 0: 720: 65.54		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		126421 ACSL3_HUMAN (1-711): 0: 720: 65.54		RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98