HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: CXAR (P97792)
Coxsackievirus and adenovirus receptor homolog (CAR) (mCAR)
Gene: Cxadr

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	12468544
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Mm			1 365
+	Hs
		940504 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Hs
		940491 LNX2_HUMAN (5-728): 2.59e-111: 354: 45.77		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Mm
		250622 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		HECAM_MOUSE (3-337): 1.36e-23: 102: 19.14
+	Mm
		956922 LNX2_MOUSE (4-728): 1.69e-87: 291: 38.25		CXAR_MOUSE (1-365): 4.24e-79: 248: 100.00
+	Hs
		1252373 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		NRCAM_HUMAN (2-362): 2.33e-24: 106: 10.50
+	Hs
		940411 DLG1_HUMAN (366-728): 8.86e-34: 140: 17.71		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Hs
		940421 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Hs
		940410 PTN13_HUMAN (356-725): 8.24e-23: 107: 14.06		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Hs
		940506 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		CXAR_HUMAN (1-365): 8.61e-78: 245: 89.86
+	Rn
		1337448 PARD3_RAT (206-555): 2.11e-31: 134: 19.33		JAM1_RAT (3-297): 1.72e-49: 170: 19.87
+	Hs
		1256929 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		JAM1_HUMAN (1-296): 5.73e-53: 178: 19.54
+	Mm
		292319 MPDZ_MOUSE (242-360): 1.05e-17: 90.5: 26.89		JAM1_MOUSE (3-297): 4.33e-47: 163: 20.52
+	Mm
		1195001 DLG1_MOUSE (334-728): 2.83e-34: 142: 16.29		NRCAM_MOUSE (11-337): 6.7e-26: 111: 13.17
+	Hs
		883798 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		JAM2_HUMAN (26-223): 9.52e-31: 120: 23.22
+	Hs
		1256876 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		JAM3_HUMAN (27-264): 1.67e-29: 117: 21.91
+	Mm
		1143386 DLG4_MOUSE (578-726): 1.86e-21: 101: 19.21		NRCAM_MOUSE (11-337): 6.7e-26: 111: 13.17
+	Hs
		1050029 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		LRIG1_HUMAN (19-137): 2.01e-10: 64.3: 17.65
+	Hs
		1136434 MAGI3_HUMAN (324-725): 9.53e-17: 87: 13.59		NRCAM_HUMAN (2-362): 2.33e-24: 106: 10.50
+	Mm
		936319 DLG4_MOUSE (578-726): 1.86e-21: 101: 19.21		DCC_MOUSE (127-338): 1.19e-10: 65.3: 11.89
+	Hs
		1256852 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		TITIN_HUMAN (134-365): 7.17e-09: 60: 11.11