HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: LIPB1 (Q8C8U0)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1)
Gene: Ppfibp1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~SAM_1
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 728 Mm			1 969
+	Mm
		250623 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		KAZRN_MOUSE (154-919): 4.73e-68: 244: 19.47
+	Hs
		1202996 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		LIPB1_HUMAN (1-969): 4.77e-155: 485: 85.86
+	Mm
		1149111 LNX2_MOUSE (4-728): 1.69e-87: 291: 38.25		KAZRN_MOUSE (154-919): 4.73e-68: 244: 19.47
+	Mm
		250603 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		LIPA3_MOUSE (23-620): 1.29e-13: 77.6: 10.64
+	Mm
		250638 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		LIPA2_MOUSE (64-557): 6.45e-10: 65.6: 9.38
+	Mm
		71321 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		B2RXW8_MOUSE (46-669): 3.28e-09: 63.3: 9.19
+	Mm
		400 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		A0A087WPM2_MOUSE (39-475): 5.26e-09: 62.6: 11.73
+	Hs
		724926 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		MYH9_HUMAN (15-419): 1.95e-14: 80.3: 8.87
+	Hs
		255251 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		LIPA3_HUMAN (37-423): 2.5e-12: 73.3: 9.95
+	Hs
		1025322 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		LIPA1_HUMAN (18-378): 2.62e-11: 69.9: 11.36
+	Rn
		957056 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		LIPA3_RAT (18-394): 4.03e-12: 72.6: 11.39
+	Rn
		88835 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		D3ZZ81_RAT (2-514): 3.34e-11: 69.5: 8.58
+	Rn
		957057 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		LIPA4_RAT (83-411): 2.87e-09: 63.3: 10.94
+	Rn
		1265269 GRIP2_RAT (326-720): 7.34e-36: 147: 19.66		LIPA4_RAT (83-411): 2.87e-09: 63.3: 10.94
+	Hs
		1025339 GRIP2_HUMAN (314-495): 7.13e-09: 61.4: 21.13		LIPA1_HUMAN (18-378): 2.62e-11: 69.9: 11.36