HitPredict

Interactor 1: CSKP (O70589)
Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase)
Gene: Cask

Interactor 2: LIN7B (O88951)
Protein lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2)
Gene: LIN7B

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19022416
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, L27~L27, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0016323 - basolateral plasma membrane GO:0030165 - PDZ domain binding GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 926 Mm			1 207
+	Hs
		159269 CSKP_HUMAN (1-926): 0: 967: 99.89		LIN7B_HUMAN (1-207): 2.34e-60: 189: 98.07
+	Hs
		159277 CSKP_HUMAN (1-926): 0: 967: 99.89		LIN7C_HUMAN (1-196): 6.24e-56: 177: 85.71
+	Mm
		251090 CSKP_MOUSE (1-926): 0: 967: 100.00		LIN7C_MOUSE (1-196): 6.24e-56: 177: 85.71
+	Hs
		158254 CSKP_HUMAN (1-926): 0: 967: 99.89		LIN7A_HUMAN (4-194): 8.7e-52: 168: 79.58
+	Hs
		159203 CSKP_HUMAN (1-926): 0: 967: 99.89		SNTB2_HUMAN (2-207): 8.23e-36: 133: 27.62
+	Hs
		159207 CSKP_HUMAN (1-926): 0: 967: 99.89		SNTB1_HUMAN (2-206): 3.35e-34: 129: 24.41
+	Hs
		159110 CSKP_HUMAN (1-926): 0: 967: 99.89		CSKP_HUMAN (10-206): 2.39e-32: 124: 19.51
+	Hs
		159190 CSKP_HUMAN (1-926): 0: 967: 99.89		DLG4_HUMAN (24-204): 3.06e-24: 101: 20.97
+	Hs
		159200 CSKP_HUMAN (1-926): 0: 967: 99.89		DLG1_HUMAN (60-181): 1.19e-23: 99.7: 30.71
+	Mm
		251104 CSKP_MOUSE (1-926): 0: 967: 100.00		DLG1_MOUSE (67-191): 6.56e-23: 97.8: 30.53
+	Hs
		159249 CSKP_HUMAN (1-926): 0: 967: 99.89		DLG3_HUMAN (93-164): 4.17e-19: 86.8: 38.96
+	Rn
		1144009 CSKP_RAT (1-926): 0: 940: 97.84		DLG1_RAT (67-191): 7.81e-23: 97.4: 28.46
+	Dm
		1096800 CSKP_DROME (1-926): 0: 831: 60.38		Q9VBY7_DROME (1-195): 1.04e-52: 169: 77.95
+	Ce
		873636 LIN2_CAEEL (2-926): 0: 738: 45.31		Q9U245_CAEEL (2-206): 4.04e-47: 155: 62.93
+	Dm
		116476 M9PJD0_DROME (287-926): 3.02e-154: 500: 24.89		Q9VBY7_DROME (1-195): 1.04e-52: 169: 77.95
+	Mm
		936188 DLG3_MOUSE (401-922): 6.89e-153: 473: 22.97		DLG2_MOUSE (24-202): 7.91e-27: 109: 21.74
+	Mm
		936180 DLG3_MOUSE (401-922): 6.89e-153: 473: 22.97		DLG4_MOUSE (24-204): 1.45e-24: 102: 20.97
+	Rn
		677790 DLG3_RAT (401-922): 6.6e-153: 473: 22.97		DLG4_RAT (24-204): 3.01e-24: 101: 20.97
+	Rn
		1144010 DLG3_RAT (401-922): 6.6e-153: 473: 22.97		DLG1_RAT (67-191): 7.81e-23: 97.4: 28.46
+	Dm
		53136 A1Z8G0_DROME (364-925): 1.66e-150: 459: 28.95		DLG1_DROME (2-200): 1.79e-15: 76: 20.57