Protein: KLRD1
Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)

Gene: KLRD1
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q13241

Gene Ontology (top 5):
GO:0001915 - negative regulation of T cell mediated cytotoxicity
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002228 - natural killer cell mediated immunity
GO:0002250 - adaptive immune response
GO:0004888 - transmembrane signaling receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

688554

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

7

18

Small-scale

0.960

High

688661

NKG2C
NKG2-C type II integral membrane protein

5

16

Small-scale

0.909

High

568059

HLAE
HLA class I histocompatibility antigen, alpha chain E

2

20

Small-scale

0.768

High

963503

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

2

20

Small-scale

0.754

High

520827

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

High-throughput

0.691

High

1009143

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

20

High-throughput

0.691

High

1022383

IDD
Integral membrane protein DGCR2/IDD

1

11

High-throughput

0.691

High

1098935

CNTP3
Contactin-associated protein-like 3

1

12

High-throughput

0.691

High

1059313

NKG2E
NKG2-E type II integral membrane protein

1

16

Small-scale

0.618

High

380019

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

20

High-throughput

0.575

High

61104

T131L
Transmembrane protein 131-like

1

2

High-throughput

0.536

High

161027

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

High-throughput

0.536

High

366487

UROK
Urokinase-type plasminogen activator

1

4

High-throughput

0.536

High

565611

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

10

High-throughput

0.536

High

571233

PERF
Perforin-1

1

1

High-throughput

0.536

High

698624

CALX
Calnexin

1

20

High-throughput

0.536

High

723682

NTR1
Neurotensin receptor type 1

1

5

High-throughput

0.536

High

787392

TGFR1
TGF-beta receptor type-1

1

5

High-throughput

0.536

High

905556

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

High-throughput

0.536

High

1023427

AT8B2
Phospholipid-transporting ATPase ID

1

7

High-throughput

0.536

High

1032577

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

8

High-throughput

0.536

High

1034223

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

9

High-throughput

0.536

High

1043120

TAP1
Antigen peptide transporter 1

1

11

High-throughput

0.536

High

1047213

ATP7A
Copper-transporting ATPase 1

1

8

High-throughput

0.536

High

1098901

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

1

High-throughput

0.536

High

1098905

CNNM4
Metal transporter CNNM4

1

5

High-throughput

0.536

High

1098908

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.536

High

1098910

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

9

High-throughput

0.536

High

1098913

AGRG6
Adhesion G-protein coupled receptor G6

1

9

High-throughput

0.536

High

1098919

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

1

14

High-throughput

0.536

High

1098923

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

5

High-throughput

0.536

High

1098927

CTR3
Cationic amino acid transporter 3

1

9

High-throughput

0.536

High

1098929

NICA
Nicastrin

1

1

High-throughput

0.536

High

1098933

S39A3
Zinc transporter ZIP3

1

7

High-throughput

0.536

High

1098936

ABCA2
ATP-binding cassette sub-family A member 2

1

3

High-throughput

0.536

High

1098937

OSBL6
Oxysterol-binding protein-related protein 6

1

3

High-throughput

0.536

High

1098939

SEM6B
Semaphorin-6B

1

11

High-throughput

0.536

High

1098940

OSBL3
Oxysterol-binding protein-related protein 3

1

3

High-throughput

0.536

High

1098943

RHOF
Rho-related GTP-binding protein RhoF

1

15

High-throughput

0.536

High

1098945

ABCB6
ATP-binding cassette sub-family B member 6

1

7

High-throughput

0.536

High

1098948

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.536

High

1098950

PLXA1
Plexin-A1

1

17

High-throughput

0.536

High

1098952

XCT
Cystine/glutamate transporter

1

9

High-throughput

0.536

High

1098953

S27A6
Long-chain fatty acid transport protein 6

1

1

High-throughput

0.536

High

1098891

TMED1
Transmembrane emp24 domain-containing protein 1

1

0

High-throughput

0.513

High

161870

IMPA2
Inositol monophosphatase 2

1

1

High-throughput

0.489

High

170747

CLGN
Calmegin

1

20

High-throughput

0.489

High

228078

PM34
Peroxisomal membrane protein PMP34

1

10

High-throughput

0.489

High

251080

B4GT3
Beta-1,4-galactosyltransferase 3

1

4

High-throughput

0.489

High

281203

CDC45
Cell division control protein 45 homolog

1

1

High-throughput

0.489

High

322724

RHBT3
Rho-related BTB domain-containing protein 3

1

15

High-throughput

0.489

High

337256

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

9

High-throughput

0.489

High

354964

CHK2
Serine/threonine-protein kinase Chk2

1

4

High-throughput

0.489

High

829202

RFC3
Replication factor C subunit 3

1

1

High-throughput

0.489

High

894466

PPOX
Protoporphyrinogen oxidase

1

1

High-throughput

0.489

High

944798

PCBP3
Poly(rC)-binding protein 3

1

1

High-throughput

0.489

High

1043203

TAP2
Antigen peptide transporter 2

1

11

High-throughput

0.489

High

1084039

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

8

High-throughput

0.489

High

1098892

ATR
Serine/threonine-protein kinase ATR

1

5

High-throughput

0.489

High

1098894

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

3

High-throughput

0.489

High

1098895

TBB8
Tubulin beta-8 chain

1

10

High-throughput

0.489

High

1098896

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

10

High-throughput

0.489

High

1098898

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

8

High-throughput

0.489

High

1098899

METRL
Meteorin-like protein

1

2

High-throughput

0.489

High

1098900

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

9

High-throughput

0.489

High

1098902

HEAT6
HEAT repeat-containing protein 6

1

3

High-throughput

0.489

High

1098903

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

5

High-throughput

0.489

High

1098904

ACD10
Acyl-CoA dehydrogenase family member 10

1

2

High-throughput

0.489

High

1098906

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

7

High-throughput

0.489

High

1098907

NFXL1
NF-X1-type zinc finger protein NFXL1

1

13

High-throughput

0.489

High

1098911

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

8

High-throughput

0.489

High

1098912

SCD5
Stearoyl-CoA desaturase 5

1

2

High-throughput

0.489

High

1098914

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

10

High-throughput

0.489

High

1098917

K2013
Uncharacterized protein KIAA2013

1

2

High-throughput

0.489

High

1098918

CHSTE
Carbohydrate sulfotransferase 14

1

5

High-throughput

0.489

High

1098920

MROH1
Maestro heat-like repeat-containing protein family member 1

1

4

High-throughput

0.489

High

1098922

ZNT7
Zinc transporter 7

1

7

High-throughput

0.489

High

1098924

GPX8
Probable glutathione peroxidase 8

1

6

High-throughput

0.489

High

1098925

NEUFC
Neuferricin

1

3

High-throughput

0.489

High

1098926

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.489

High

1098928

ELYS
Protein ELYS

1

2

High-throughput

0.489

High

1098930

S35E1
Solute carrier family 35 member E1

1

1

High-throughput

0.489

High

1098931

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

11

High-throughput

0.489

High

1098932

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.489

High

1098934

SFXN3
Sideroflexin-3

1

4

High-throughput

0.489

High

1098938

TM39B
Transmembrane protein 39B

1

2

High-throughput

0.489

High

1098941

NSUN3
tRNA

1

1

High-throughput

0.489

High

1098942

AT133
Polyamine-transporting ATPase 13A3

1

12

High-throughput

0.489

High

1098944

K1586
E3 SUMO-protein ligase KIAA1586

1

2

High-throughput

0.489

High

1098946

FANCI
Fanconi anemia group I protein

1

3

High-throughput

0.489

High

1098947

ARL8B
ADP-ribosylation factor-like protein 8B

1

6

High-throughput

0.489

High

1098949

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

4

High-throughput

0.489

High

1098951

METRN
Meteorin

1

2

High-throughput

0.489

High

230960

TYOBP
TYRO protein tyrosine kinase-binding protein

1

3

Small-scale

0.479

High

177541

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.279

Low

660259

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.279

Low

895237

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.279

Low

1098893

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

1098897

P5CR3
Pyrroline-5-carboxylate reductase 3

1

0

High-throughput

0.279

Low

1098909

INT8
Integrator complex subunit 8

1

0

High-throughput

0.279

Low

1098915

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.279

Low

1098916

T183A
Transmembrane protein 183A

1

0

High-throughput

0.279

Low

1098921

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025