HitPredict

Interactor 1: WAT1 (O74184)
Target of rapamycin complex subunit wat1 (TORC subunit wat1) (WD repeat-containing protein pop3)
Gene: pop3

Interactor 2: U2AF2 (P36629)
Splicing factor U2AF 59 kDa subunit (U2 auxiliary factor 59 kDa subunit) (U2AF59) (U2 snRNP auxiliary factor large subunit)
Gene: prp2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	11686295, 24586893
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 314 Sp			1 517
+	Hs
		641697 WDR5_HUMAN (202-311): 6.44e-29: 115: 29.09		U2AF2_HUMAN (113-517): 6.48e-69: 230: 28.85
+	Hs
		641889 SNR40_HUMAN (199-307): 1.06e-25: 106: 22.02		U2AF2_HUMAN (113-517): 6.48e-69: 230: 28.85
+	Hs
		196958 PRP4_HUMAN (196-311): 3.01e-19: 89.6: 23.85		U2AF2_HUMAN (113-517): 6.48e-69: 230: 28.85
+	Hs
		903196 WDR5_HUMAN (202-311): 6.44e-29: 115: 29.09		PABP4_HUMAN (55-474): 7.41e-56: 199: 10.39
+	Hs
		516438 WDR5_HUMAN (202-311): 6.44e-29: 115: 29.09		PABP1_HUMAN (55-441): 2.15e-54: 195: 10.20
+	Hs
		1054500 SNR40_HUMAN (199-307): 1.06e-25: 106: 22.02		RBM39_HUMAN (85-423): 6.36e-20: 94.9: 17.54
+	Hs
		197019 PRP4_HUMAN (196-311): 3.01e-19: 89.6: 23.85		RBM39_HUMAN (85-423): 6.36e-20: 94.9: 17.54
+	Hs
		903585 WDR5_HUMAN (202-311): 6.44e-29: 115: 29.09		PUF60_HUMAN (417-512): 1.59e-11: 68.7: 21.65