HitPredict

Interactor 1: MITF (O75030)
Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32)
Gene: MITF

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	16029420, 22012259, 15507434
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 101
+	Hs
		585647 TFE3_HUMAN (4-521): 1.13e-65: 224: 47.87		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		585114 TFEB_HUMAN (53-523): 5.41e-58: 201: 40.08		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Mm
		928250 SRBP1_MOUSE (81-523): 8.33e-43: 165: 17.18		SUMO1_MOUSE (1-101): 1.01e-41: 134: 100.00
+	Sc
		1015429 HMS1_YEAST (34-410): 3.83e-44: 163: 17.12		SMT3_YEAST (3-99): 7.04e-32: 109: 47.42