HitPredict

Interactor 1: PLXA2 (O75051)
Plexin-A2 (Semaphorin receptor OCT)
Gene: PLXNA2

Interactor 2: SIA8D (Q92187)
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV)
Gene: ST8SIA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1894 Hs			1 359
+	Hs
		1265359 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		SIA8D_HUMAN (1-359): 2.56e-155: 442: 100.00
+	Hs
		850488 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		SIA8D_HUMAN (1-359): 2.56e-155: 442: 100.00
+	Hs
		180153 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		SIA8E_HUMAN (70-356): 6.17e-102: 307: 33.33
+	Hs
		165229 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		SIA8D_HUMAN (1-359): 2.56e-155: 442: 100.00
+	Hs
		1265342 SEM4D_HUMAN (16-563): 3.7e-117: 395: 16.72		SIA8D_HUMAN (1-359): 2.56e-155: 442: 100.00
+	Hs
		180122 RON_HUMAN (810-1205): 1.3e-87: 318: 23.37		SIA8E_HUMAN (70-356): 6.17e-102: 307: 33.33