HitPredict

Interactor 1: MTG16 (O75081)
Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)
Gene: CBFA2T3

Interactor 2: MTG8 (Q06455)
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)
Gene: RUNX1T1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	12242670, 14703694, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NHR2~NHR2, TAFH~TAFH, zf-MYND~zf-MYND
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006351 - DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 653 Hs			1 604
+	Hs
		203431 MTG16_HUMAN (1-653): 0: 1003: 100.00		MTG8R_HUMAN (32-591): 0: 778: 64.77
+	Hs
		987407 MTG8_HUMAN (54-653): 0: 846: 69.67		MTG8_HUMAN (1-604): 0: 935: 100.00
+	Hs
		203448 MTG8_HUMAN (54-653): 0: 846: 69.67		MTG8R_HUMAN (32-591): 0: 778: 64.77
+	Hs
		203429 MTG8R_HUMAN (53-641): 0: 841: 57.64		MTG8R_HUMAN (32-591): 0: 778: 64.77
+	Hs
		263405 DEAF1_HUMAN (525-595): 1.11e-25: 113: 37.66		DEAF1_HUMAN (464-574): 1.51e-29: 125: 34.23