HitPredict

Interactor 1: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31871319
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Rho_Binding
Common GO terms GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1388
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024