HitPredict

Interactor 1: LIPA3 (O75145)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: PPFIA3

Interactor 2: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~Y_phosphatase
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 1912
+	Hs
		255244 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		PTPRS_HUMAN (1-1912): 0: 1555: 71.33
+	Hs
		616970 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PTPRD_HUMAN (1-1912): 0: 1640: 100.00
+	Hs
		259637 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		PTPRD_HUMAN (1-1912): 0: 1640: 100.00
+	Hs
		255234 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		PTPRF_HUMAN (1-1912): 0: 1497: 67.03
+	Hs
		1025279 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PTPRS_HUMAN (1-1912): 0: 1555: 71.33
+	Hs
		259643 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		PTPRS_HUMAN (1-1912): 0: 1555: 71.33
+	Hs
		489956 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PTPRF_HUMAN (1-1912): 0: 1497: 67.03
+	Hs
		259635 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		PTPRF_HUMAN (1-1912): 0: 1497: 67.03
+	Dm
		65322 A8DYM0_DROME (820-1158): 5.99e-98: 340: 33.81		LAR_DROME (13-1352): 5.19e-168: 566: 33.33
+	Dm
		114417 M9PCD4_DROME (1-1118): 3.24e-75: 274: 36.17		LAR_DROME (13-1352): 5.19e-168: 566: 33.33
+	Dm
		561777 Q9VM93_DROME (1-1118): 2.83e-75: 274: 36.17		LAR_DROME (13-1352): 5.19e-168: 566: 33.33