Protein: DLG1
Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97)

Gene: DLG1
Organism: Mus musculus
Interactions: 37
UniProt ID: Q811D0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001657 - ureteric bud development
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0001771 - immunological synapse formation
GO:0001772 - immunological synapse

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223608

DLG4
Disks large homolog 4

5

17

High-throughput

0.922

High

104585

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

11

High-throughput

0.861

High

1193811

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

17

High-throughput

0.789

High

1282975

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

13

High-throughput

0.691

High

1283506

NRCAM
Neuronal cell adhesion molecule

1

10

Small-scale

0.683

High

267274

CSKP
Peripheral plasma membrane protein CASK

1

16

Small-scale

0.618

High

313202

LIN7C
Protein lin-7 homolog C

1

20

Small-scale

0.618

High

440284

LCK
Proto-oncogene tyrosine-protein kinase LCK

1

15

Small-scale

0.618

High

849106

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.618

High

1190167

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

8

High-throughput

0.618

High

1247106

NEB2
Neurabin-2

1

20

High-throughput

0.618

High

1283515

DLGP1
Disks large-associated protein 1

2

20

High-throughput

0.611

High

1281877

LRFN2
Leucine-rich repeat and fibronectin type-III domain-containing protein 2

1

15

Small-scale

0.611

High

205069

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

2

11

Small-scale

0.584

High

312837

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.536

High

1013648

TNIK
Traf2 and NCK-interacting protein kinase

1

16

High-throughput

0.536

High

1180772

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

15

Small-scale

0.528

High

73150

SCN7A
Sodium channel protein type 7 subunit alpha

1

3

Small-scale

0.479

High

97444

PRRT2
Proline-rich transmembrane protein 2

1

4

High-throughput

0.479

High

147832

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

5

Small-scale

0.479

High

651550

CBL
E3 ubiquitin-protein ligase CBL

1

4

Small-scale

0.479

High

771492

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

20

High-throughput

0.479

High

867757

MK14
Mitogen-activated protein kinase 14

1

8

Small-scale

0.479

High

1000085

WASP
Actin nucleation-promoting factor WAS

1

3

Small-scale

0.479

High

1221725

SC6A4
Sodium-dependent serotonin transporter

1

9

High-throughput

0.479

High

1243458

KIF11
Kinesin-like protein KIF11

1

15

Small-scale

0.479

High

1283516

GBG13

1

1

Small-scale

0.479

High

266973

FZD1
Frizzled-1

1

13

Small-scale

0.457

High

1222287

FZD4
Frizzled-4

1

13

Small-scale

0.457

High

1222293

FZD7
Frizzled-7

1

13

Small-scale

0.457

High

1223157

GRID2
Glutamate receptor ionotropic, delta-2

1

20

Small-scale

0.457

High

777951

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.445

High

1029222

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

20

High-throughput

0.445

High

1135308

PTHD1
Patched domain-containing protein 1

1

6

Small-scale

0.445

High

148485

MK12
Mitogen-activated protein kinase 12

1

8

Small-scale

0.437

High

1283513

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

10

High-throughput

0.437

High

1283514

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.437

High


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Last updated: 11Aug2025