HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014704 - intercalated disc
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1896 Hs			1 2871
+	Hs
		255591 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		CENPF_HUMAN (11-1800): 6.64e-55: 215: 10.64
+	Hs
		255802 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33
+	Hs
		255701 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10
+	Hs
		255785 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08
+	Hs
		255631 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71
+	Hs
		256153 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38
+	Hs
		551790 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		DESP_HUMAN (1-2871): 0: 818: 100.00
+	Hs
		234520 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33
+	Hs
		234503 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10
+	Hs
		234502 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93
+	Hs
		234595 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38
+	Mm
		250933 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		MYH6_MOUSE (1381-2029): 3.04e-31: 137: 15.52
+	Hs
		522615 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		MYH7_HUMAN (38-718): 1.99e-21: 105: 8.44
+	Mm
		250946 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		MACF1_MOUSE (1987-2820): 1.6e-10: 69.5: 12.38
+	Hs
		1068678 MXRA5_HUMAN (1-97): 5.61e-10: 67: 17.35		PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33
+	Hs
		528411 MYPC2_HUMAN (1733-1894): 4.1e-09: 63.9: 25.90		MYH8_HUMAN (45-861): 4.24e-26: 120: 9.54
+	Hs
		974073 MYPC2_HUMAN (1733-1894): 4.1e-09: 63.9: 25.90		DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10
+	Dm
		54348 Q9W053_DROME (896-975): 1.27e-09: 65.8: 19.75		A1Z9J3_DROME (1081-2245): 1.95e-14: 82.6: 11.82