HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1896 Hs			1 2725
+	Hs
		1052877 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		FLNC_HUMAN (1-2725): 0: 2507: 100.00
+	Hs
		255501 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		255374 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		234453 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		255470 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211438 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		255932 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		255957 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Mm
		1161055 MYLK_MOUSE (1626-1708): 5.61e-10: 67: 22.35		FLNB_MOUSE (146-2725): 0: 1194: 34.74
+	Hs
		234468 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211436 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		234502 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		234551 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Dm
		574825 TITIN_DROME (1-99): 1.34e-09: 65.8: 22.00		ACTN_DROME (1-386): 1.84e-105: 364: 25.90
+	Hs
		363077 PGBM_HUMAN (1519-1650): 8.15e-10: 66.6: 17.33		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		1060200 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Ce
		136802 UNC22_CAEEL (11-99): 1.27e-09: 65.8: 22.47		UNC89_CAEEL (406-2706): 4.03e-33: 144: 10.48
+	Dm
		65342 OBSCN_DROME (655-985): 3.05e-11: 71.2: 8.33		Q9W4Y3_DROME (1165-1441): 2.79e-17: 92.1: 10.86
+	Hs
		962510 MYPC1_HUMAN (7-99): 4.98e-17: 90.1: 24.73		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Hs
		1137771 OBSCN_HUMAN (1359-1557): 1.25e-10: 69.3: 18.54		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78