Interactor 1: NDUS2 (O75306)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)
Gene: NDUFS2

Interactor 2: NDUS3 (O75489)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit)
Gene: NDUFS3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 24344204, 27499296, 28514442, 33961781, 37071682, 15250827, 19688755
Identification Methods affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation, blue native page, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Complex1_30kDa~Complex1_49kDa
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 463
Hs

1 264
+ Ss
+ Ec
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024