HitPredict

Interactor 1: LIPA2 (O75334)
Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2)
Gene: PPFIA2

Interactor 2: LIPB2 (Q8ND30)
Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2)
Gene: PPFIBP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2
Common GO terms	GO:0005829 - cytosol GO:0048786 - presynaptic active zone
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1257 Hs			1 876
+	Hs
		1025318 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPB2_HUMAN (1-876): 1.36e-162: 498: 100.00
+	Hs
		259650 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Hs
		255249 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Hs
		1025311 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPB1_HUMAN (1-875): 2.93e-95: 323: 40.56
+	Dm
		65321 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		A8DYM0_DROME (173-856): 1.3e-95: 326: 23.07
+	Dm
		65319 A8DYM0_DROME (877-1229): 3.16e-88: 313: 31.03		A8DYM0_DROME (173-856): 1.3e-95: 326: 23.07
+	Dm
		114427 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		Q9VU88_DROME (279-842): 7.16e-78: 268: 30.65
+	Hs
		259634 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPA2_HUMAN (62-564): 5.06e-11: 68.9: 12.03
+	Hs
		255231 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPA3_HUMAN (51-424): 1.08e-10: 67.8: 13.60
+	Hs
		259642 LIPA2_HUMAN (1-1257): 1.83e-152: 493: 100.00		LIPA1_HUMAN (4-331): 5.55e-09: 62.4: 12.81
+	Hs
		1146483 KAZRN_HUMAN (439-1215): 5.66e-74: 264: 19.72		KAZRN_HUMAN (114-797): 6.64e-58: 214: 21.23
+	Hs
		255230 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPA3_HUMAN (51-424): 1.08e-10: 67.8: 13.60
+	Hs
		255242 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		LIPA1_HUMAN (4-331): 5.55e-09: 62.4: 12.81
+	Hs
		1025277 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		LIPA1_HUMAN (4-331): 5.55e-09: 62.4: 12.81
+	Dm
		114416 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		M9PCD4_DROME (51-474): 3.98e-12: 72.3: 12.26