Protein: HCF
Host cell factor (dHcf) [Cleaved into: HCF N-terminal chain; HCF C-terminal chain]

Gene: HCF
Organism: Drosophila melanogaster
Interactions: 38
UniProt ID: Q9V4C8

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1269020

TAD2A
Transcriptional adapter 2A

4

1

Small-scale

0.686

High

1465348

DPOE3
DNA polymerase epsilon subunit 3

4

1

Small-scale

0.686

High

1465788

Q9VJ73
Ada2a-containing complex component 2

4

5

Small-scale

0.686

High

1465785

MOC2B
Molybdopterin synthase catalytic subunit

3

2

Small-scale

0.656

High

1465791

Q9VLL1
D12

3

3

Small-scale

0.650

High

1463901

WDS
Protein will die slowly

3

5

Small-scale

0.640

High

1375064

ASH2
Set1/Ash2 histone methyltransferase complex subunit ASH2

3

9

Small-scale

0.633

High

122200

M9PHZ1
Transcriptional adaptor 3, isoform C

2

1

Small-scale

0.584

High

1465793

Q9VM59
Ada2a-containing complex component 1

2

3

Small-scale

0.584

High

1465794

Q9VTZ1
histone acetyltransferase

2

8

Small-scale

0.584

High

1465799

MYC
Myc proto-oncogene protein

1

7

Small-scale

0.561

High

1208006

SET1
Histone-lysine N-methyltransferase SETD1

1

20

Small-scale

0.554

High

120175

M9PCJ7
Utx histone demethylase, isoform E

1

6

Small-scale

0.479

High

896161

MSL3
Protein male-specific lethal-3

1

1

Small-scale

0.479

High

1173345

DIAP2
Death-associated inhibitor of apoptosis 2

1

2

High-throughput

0.479

High

1216740

Q5U0Y0
Paired amphipathic helix protein Sin3a

1

5

Small-scale

0.479

High

1302162

TAD2B
Transcriptional adapter 2b

1

1

Small-scale

0.479

High

1306741

TRR
Histone-lysine N-methyltransferase trr

1

20

Small-scale

0.479

High

1374911

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

5

High-throughput

0.479

High

1465787

MBDR2
Protein MBD-R2

1

11

High-throughput

0.479

High

1465789

NC2B
Protein Dr1

1

1

High-throughput

0.479

High

1465792

WDR82
WD repeat-containing protein 82

1

12

Small-scale

0.479

High

1428049

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

1465797

Q9VYZ8
GEO08286p1

1

0

Small-scale

0.458

High

1465798

SGF29
SAGA-associated factor 29kDa

1

0

High-throughput

0.458

High

1306768

CASP8
Caspase-8

1

3

High-throughput

0.437

High

1427714

PGPLC
Peptidoglycan-recognition protein LC

1

1

High-throughput

0.437

High

1464140

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

5

High-throughput

0.437

High

1465786

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

15

High-throughput

0.437

High

1465796

PGPLE
Peptidoglycan-recognition protein LE

1

1

High-throughput

0.437

High

1175069

NETB
Netrin-B

1

3

High-throughput

0.407

High

1465790

Q9VJW9
ADAM10 endopeptidase

1

1

High-throughput

0.407

High

1237455

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

1261819

Q7JRH2
Receptor expression-enhancing protein

1

0

High-throughput

0.249

Low

1266720

IMD
Protein immune deficiency

1

0

High-throughput

0.249

Low

1377342

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

1463192

FADD
Fas-associated death domain protein

1

0

High-throughput

0.249

Low

1465795

Q9VWJ4
LD24910p

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025