Protein: TMED2
Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1)

Gene: TMED2
Organism: Homo sapiens
Interactions: 199
UniProt ID: Q15363

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001843 - neural tube closure
GO:0001893 - maternal placenta development
GO:0001947 - heart looping
GO:0005109 - frizzled binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833223

TMEDA
Transmembrane emp24 domain-containing protein 10

9

17

Small-scale

0.966

High

1071863

TMED7
Transmembrane emp24 domain-containing protein 7

5

18

Small-scale

0.916

High

1071784

TMED4
Transmembrane emp24 domain-containing protein 4

4

17

High-throughput

0.903

High

1034786

TMED1
Transmembrane emp24 domain-containing protein 1

3

17

High-throughput

0.871

High

1071862

TMED5
Transmembrane emp24 domain-containing protein 5

3

17

High-throughput

0.871

High

1071864

TMED3
Transmembrane emp24 domain-containing protein 3

3

17

High-throughput

0.861

High

1071826

TMED9
Transmembrane emp24 domain-containing protein 9

3

17

Small-scale

0.855

High

1071841

GORS2
Golgi reassembly-stacking protein 2

3

16

Small-scale

0.683

High

1071837

CHST8
Carbohydrate sulfotransferase 8

3

6

High-throughput

0.667

High

1071792

EMC1
ER membrane protein complex subunit 1

3

4

High-throughput

0.650

High

958355

AT8B2
Phospholipid-transporting ATPase ID

2

3

High-throughput

0.628

High

1059216

GOGB1
Golgin subfamily B member 1

2

3

High-throughput

0.628

High

1071789

FGRL1
Fibroblast growth factor receptor-like 1

2

3

High-throughput

0.628

High

1071829

OSBL6
Oxysterol-binding protein-related protein 6

2

4

High-throughput

0.628

High

1071859

PA2G4
Proliferation-associated protein 2G4

2

2

High-throughput

0.628

High

1071865

LIPG
Endothelial lipase

2

5

High-throughput

0.628

High

1071765

TMED2
Transmembrane emp24 domain-containing protein 2

1

17

Small-scale

0.618

High

173715

SURF4
Surfeit locus protein 4

2

4

Small-scale

0.612

High

216240

CALU
Calumenin

2

4

High-throughput

0.611

High

994885

GOGA2
Golgin subfamily A member 2

2

4

Small-scale

0.611

High

876125

PAR2
Proteinase-activated receptor 2

2

7

Small-scale

0.608

High

1071799

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

2

0

High-throughput

0.602

High

1071814

CALR3
Calreticulin-3

2

9

High-throughput

0.584

High

254336

ATP9A
Probable phospholipid-transporting ATPase IIA

2

3

High-throughput

0.574

High

871906

AT12A
Potassium-transporting ATPase alpha chain 2

2

5

High-throughput

0.574

High

1071815

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

5

High-throughput

0.574

High

1071819

GORS1
Golgi reassembly-stacking protein 1

1

15

Small-scale

0.573

High

369653

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

502128

BIP
Endoplasmic reticulum chaperone BiP

2

6

High-throughput

0.571

High

592270

RAB5A
Ras-related protein Rab-5A

2

10

High-throughput

0.571

High

1062520

EMC2
ER membrane protein complex subunit 2

2

4

High-throughput

0.571

High

1071802

ATLA1
Atlastin-1

2

8

Small-scale

0.571

High

1071854

VAPA
Vesicle-associated membrane protein-associated protein A

2

10

High-throughput

0.571

High

123605

PGRC1
Membrane-associated progesterone receptor component 1

1

5

High-throughput

0.536

High

206480

B4GA1
Beta-1,4-glucuronyltransferase 1

1

2

High-throughput

0.536

High

234623

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

3

High-throughput

0.536

High

245496

NSMA
Sphingomyelin phosphodiesterase 2

1

2

High-throughput

0.536

High

263245

SC22B
Vesicle-trafficking protein SEC22b

1

4

High-throughput

0.536

High

513419

FGF3
Fibroblast growth factor 3

1

7

High-throughput

0.536

High

528167

CY24A
Cytochrome b-245 light chain

1

1

High-throughput

0.536

High

654356

CALX
Calnexin

1

9

High-throughput

0.536

High

708145

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

3

High-throughput

0.536

High

714661

CNR2
Cannabinoid receptor 2

1

4

Small-scale

0.536

High

863443

COPA
Coatomer subunit alpha

1

11

High-throughput

0.536

High

891462

CTXN1
Cortexin-1

1

1

High-throughput

0.536

High

895086

RAB2A
Ras-related protein Rab-2A

1

10

High-throughput

0.536

High

918875

RAB1A
Ras-related protein Rab-1A

1

7

High-throughput

0.536

High

1013923

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.536

High

1020027

LMAN2
Vesicular integral-membrane protein VIP36

1

3

High-throughput

0.536

High

1070819

RCN1
Reticulocalbin-1

1

4

High-throughput

0.536

High

1071774

RABL3
Rab-like protein 3

1

10

High-throughput

0.536

High

1071775

STEA3
Metalloreductase STEAP3

1

1

High-throughput

0.536

High

1071776

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.536

High

1071800

SPP2B
Signal peptide peptidase-like 2B

1

6

High-throughput

0.536

High

1071801

SCFD1
Sec1 family domain-containing protein 1

1

2

High-throughput

0.536

High

1071804

YIPF5
Protein YIPF5

1

5

High-throughput

0.536

High

1071806

CCD47
PAT complex subunit CCDC47

1

2

High-throughput

0.536

High

1071812

CK5P3
CDK5 regulatory subunit-associated protein 3

1

5

High-throughput

0.536

High

1071816

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

10

High-throughput

0.536

High

1071818

MBB1A
Myb-binding protein 1A

1

4

High-throughput

0.536

High

1071822

ERP44
Endoplasmic reticulum resident protein 44

1

5

High-throughput

0.536

High

1071833

MAGT1
Magnesium transporter protein 1

1

1

High-throughput

0.536

High

1071834

RAB1B
Ras-related protein Rab-1B

1

6

High-throughput

0.536

High

1071835

LMA2L
VIP36-like protein

1

2

High-throughput

0.536

High

1071839

TMX1
Thioredoxin-related transmembrane protein 1

1

9

High-throughput

0.536

High

1071840

SG196
Protein O-mannose kinase

1

1

High-throughput

0.536

High

1071845

RAB18
Ras-related protein Rab-18

1

10

High-throughput

0.536

High

1071846

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

4

High-throughput

0.536

High

1071860

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

10

High-throughput

0.536

High

1071868

SAR1B
Small COPII coat GTPase SAR1B

1

13

High-throughput

0.536

High

1071786

ZDH13
Palmitoyltransferase ZDHHC13

1

0

High-throughput

0.513

High

781257

CASR
Extracellular calcium-sensing receptor

1

2

Small-scale

0.506

High

534192

CD59
CD59 glycoprotein

1

0

Small-scale

0.493

High

236935

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

2

High-throughput

0.489

High

1071787

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.489

High

1071824

DIDO1
Death-inducer obliterator 1

1

2

High-throughput

0.489

High

1071857

HERC5
E3 ISG15--protein ligase HERC5

1

3

High-throughput

0.489

High

148848

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

205422

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

294857

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

297861

SC24D
Protein transport protein Sec24D

1

16

Small-scale

0.479

High

315559

SC24A
Protein transport protein Sec24A

1

16

Small-scale

0.479

High

315702

SC24B
Protein transport protein Sec24B

1

16

Small-scale

0.479

High

329738

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

377339

GCR
Glucocorticoid receptor

1

11

High-throughput

0.479

High

504114

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

509664

UBL4A
Ubiquitin-like protein 4A

1

7

High-throughput

0.479

High

531840

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.479

High

626837

PAR1
Proteinase-activated receptor 1

1

6

Small-scale

0.479

High

867099

SC24C
Protein transport protein Sec24C

1

16

Small-scale

0.479

High

890166

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

1071767

SC23A
Protein transport protein Sec23A

1

16

Small-scale

0.479

High

1071770

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

1

High-throughput

0.479

High

1071771

TECT1
Tectonic-1

1

5

High-throughput

0.479

High

1071780

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

1071782

CE128
Centrosomal protein of 128 kDa

1

5

High-throughput

0.479

High

1071790

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.479

High

1071803

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1071807

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1071809

FAF2
FAS-associated factor 2

1

2

High-throughput

0.479

High

1071811

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1071836

DJC25
DnaJ homolog subfamily C member 25

1

3

High-throughput

0.479

High

1071843

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

4

High-throughput

0.479

High

1071856

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

682178

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

1071820

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.458

High

316891

KLF8
Krueppel-like factor 8

1

5

High-throughput

0.457

High

1071827

KLF16
Krueppel-like factor 16

1

4

High-throughput

0.457

High

48363

ESYT2
Extended synaptotagmin-2

1

5

High-throughput

0.445

High

50149

HACL2
2-hydroxyacyl-CoA lyase 2

1

2

High-throughput

0.445

High

58089

NBAS
NBAS subunit of NRZ tethering complex

1

2

High-throughput

0.445

High

99792

F5H6I7
Atlastin GTPase 3

1

8

High-throughput

0.445

High

149640

COPE
Coatomer subunit epsilon

1

2

High-throughput

0.445

High

199336

ZW10
Centromere/kinetochore protein zw10 homolog

1

2

High-throughput

0.445

High

202893

EMC8
ER membrane protein complex subunit 8

1

2

High-throughput

0.445

High

258929

RTN2
Reticulon-2

1

8

High-throughput

0.445

High

266162

ERLN1
Erlin-1

1

2

High-throughput

0.445

High

277066

STAM2
Signal transducing adapter molecule 2

1

3

High-throughput

0.445

High

297752

MICA2
[F-actin]-monooxygenase MICAL2

1

2

High-throughput

0.445

High

307042

RTN3
Reticulon-3

1

8

High-throughput

0.445

High

310645

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

10

High-throughput

0.445

High

335426

NB5R3
NADH-cytochrome b5 reductase 3

1

3

High-throughput

0.445

High

432727

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.445

High

532126

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

2

High-throughput

0.445

High

653599

CALR
Calreticulin

1

9

High-throughput

0.445

High

725451

COPB2
Coatomer subunit beta'

1

11

High-throughput

0.445

High

818943

COPD
Coatomer subunit delta

1

4

High-throughput

0.445

High

822029

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.445

High

847276

SSRD
Translocon-associated protein subunit delta

1

2

High-throughput

0.445

High

847482

BAP31
B-cell receptor-associated protein 31

1

4

High-throughput

0.445

High

863235

COPB
Coatomer subunit beta

1

3

High-throughput

0.445

High

902313

COPZ1
Coatomer subunit zeta-1

1

3

High-throughput

0.445

High

924005

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

2

High-throughput

0.445

High

945844

NUCB2
Nucleobindin-2

1

2

High-throughput

0.445

High

950620

ARF5
ADP-ribosylation factor 5

1

10

High-throughput

0.445

High

961666

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.445

High

1026688

PRDX4
Peroxiredoxin-4

1

2

High-throughput

0.445

High

1058427

GANAB
Neutral alpha-glucosidase AB

1

2

High-throughput

0.445

High

1065248

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

2

High-throughput

0.445

High

1065361

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

2

High-throughput

0.445

High

1071766

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.445

High

1071769

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

3

High-throughput

0.445

High

1071772

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

10

High-throughput

0.445

High

1071773

YIF1B
Protein YIF1B

1

3

High-throughput

0.445

High

1071779

LCLT1
Lysocardiolipin acyltransferase 1

1

2

High-throughput

0.445

High

1071785

TCAM2
TIR domain-containing adapter molecule 2

1

2

High-throughput

0.445

High

1071788

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

5

High-throughput

0.445

High

1071791

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

2

High-throughput

0.445

High

1071793

DHB11
Estradiol 17-beta-dehydrogenase 11

1

8

High-throughput

0.445

High

1071794

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.445

High

1071795

VP37A
Vacuolar protein sorting-associated protein 37A

1

2

High-throughput

0.445

High

1071796

ATLA2
Atlastin-2

1

8

High-throughput

0.445

High

1071797

MCFD2
Multiple coagulation factor deficiency protein 2

1

2

High-throughput

0.445

High

1071805

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

10

High-throughput

0.445

High

1071808

ASTRA
Protein Aster-A

1

2

High-throughput

0.445

High

1071813

SCYL1
N-terminal kinase-like protein

1

5

High-throughput

0.445

High

1071823

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.445

High

1071825

NDC1
Nucleoporin NDC1

1

2

High-throughput

0.445

High

1071830

WDR11
WD repeat-containing protein 11

1

2

High-throughput

0.445

High

1071831

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.445

High

1071838

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

2

High-throughput

0.445

High

1071844

APMAP
Adipocyte plasma membrane-associated protein

1

2

High-throughput

0.445

High

1071847

RTN4
Reticulon-4

1

8

High-throughput

0.445

High

1071848

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.445

High

1071853

TECR
Very-long-chain enoyl-CoA reductase

1

3

High-throughput

0.445

High

1071855

COPG2
Coatomer subunit gamma-2

1

7

High-throughput

0.445

High

1071861

DHRS7
Dehydrogenase/reductase SDR family member 7

1

5

High-throughput

0.445

High

1071867

COPG1
Coatomer subunit gamma-1

1

7

High-throughput

0.445

High

210013

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.437

High

552789

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651271

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

847775

P2RY4
P2Y purinoceptor 4

1

7

Small-scale

0.437

High

1045328

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

2

High-throughput

0.437

High

1053565

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1071777

VIR
Protein virilizer homolog

1

4

High-throughput

0.437

High

1071778

TECT3
Tectonic-3

1

5

High-throughput

0.437

High

1071781

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1071798

LNX1
E3 ubiquitin-protein ligase LNX

1

4

Small-scale

0.437

High

1071810

P2Y11
P2Y purinoceptor 11

1

8

Small-scale

0.437

High

1071828

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.437

High

1071849

T106B
Transmembrane protein 106B

1

4

High-throughput

0.437

High

1071768

SC23B
Protein transport protein Sec23B

1

16

Small-scale

0.408

High

201019

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

2

High-throughput

0.407

High

497063

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.407

High

827796

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

2

High-throughput

0.407

High

1071783

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

3

High-throughput

0.407

High

1071817

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.407

High

1071821

PXL2A
Peroxiredoxin-like 2A

1

2

High-throughput

0.407

High

1071832

RGAP1
Rac GTPase-activating protein 1

1

2

High-throughput

0.407

High

1071850

TM38B
Trimeric intracellular cation channel type B

1

2

High-throughput

0.407

High

1071851

GPTC2
G patch domain-containing protein 2

1

2

High-throughput

0.407

High

1071852

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.407

High

1071866

SERC
Phosphoserine aminotransferase

1

2

High-throughput

0.407

High

1071858

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.328

High

330317

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.279

Low

433059

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

1071842

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

779458

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024