Protein: LZTR1
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)

Gene: LZTR1
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q8N653

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0012505 - endomembrane system
GO:0016567 - protein ubiquitination
GO:0031267 - small GTPase binding
GO:0031463 - Cul3-RING ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1113693

CUL3
Cullin-3

6

20

Small-scale

0.937

High

1328741

LZTR1
Leucine-zipper-like transcriptional regulator 1

5

18

Small-scale

0.917

High

1328757

NUD12
NAD-capped RNA hydrolase NUDT12

3

7

High-throughput

0.770

High

374763

RASH
GTPase HRas

6

7

Small-scale

0.731

High

1328766

KBTB4
Kelch repeat and BTB domain-containing protein 4

2

19

High-throughput

0.726

High

374058

RASN
GTPase NRas

5

9

Small-scale

0.704

High

1328747

ASB12
Ankyrin repeat and SOCS box protein 12

1

5

High-throughput

0.698

High

375723

RASK
GTPase KRas

6

9

Small-scale

0.669

High

1328756

RIT2
GTP-binding protein Rit2

3

10

High-throughput

0.662

High

1328749

RIT1
GTP-binding protein Rit1

4

9

Small-scale

0.642

High

222147

NCK2
Cytoplasmic protein NCK2

4

5

High-throughput

0.630

High

1328742

ANR53
Ankyrin repeat domain-containing protein 53

1

4

High-throughput

0.625

High

1328744

FANK1
Fibronectin type 3 and ankyrin repeat domains protein 1

1

7

High-throughput

0.625

High

1328763

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

High-throughput

0.625

High

1328776

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

3

High-throughput

0.625

High

1114939

CUL4A
Cullin-4A

1

20

High-throughput

0.618

High

1199005

KLH12
Kelch-like protein 12

1

18

Small-scale

0.618

High

849019

PTN9
Tyrosine-protein phosphatase non-receptor type 9

3

1

High-throughput

0.609

High

952243

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

15

High-throughput

0.606

High

807499

IF4A3
Eukaryotic initiation factor 4A-III

3

10

High-throughput

0.604

High

1328761

NUAK2
NUAK family SNF1-like kinase 2

3

3

High-throughput

0.604

High

401140

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

10

Small-scale

0.584

High

1328769

GCP4
Gamma-tubulin complex component 4

2

1

High-throughput

0.584

High

240107

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

7

High-throughput

0.574

High

1328760

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

12

High-throughput

0.574

High

269966

AUXI
Auxilin

2

2

High-throughput

0.558

High

165128

RASM
Ras-related protein M-Ras

2

9

Small-scale

0.543

High

1328762

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

6

High-throughput

0.541

High

606016

CAN2
Calpain-2 catalytic subunit

1

2

High-throughput

0.536

High

1328745

PAR3L
Partitioning defective 3 homolog B

1

5

High-throughput

0.536

High

219499

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.518

High

1149826

TAF11
Transcription initiation factor TFIID subunit 11

1

0

High-throughput

0.518

High

48298

E2F8
Transcription factor E2F8

1

4

High-throughput

0.494

High

487532

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.494

High

571680

HCLS1
Hematopoietic lineage cell-specific protein

1

4

High-throughput

0.494

High

659256

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.494

High

669943

MCM3
DNA replication licensing factor MCM3

1

10

High-throughput

0.494

High

723022

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.494

High

838140

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

High-throughput

0.494

High

941016

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.494

High

1043707

CEBPZ
CCAAT/enhancer-binding protein zeta

1

1

High-throughput

0.494

High

1085447

SRBP2
Sterol regulatory element-binding protein 2

1

7

High-throughput

0.494

High

1094705

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.494

High

1095507

NR1H3
Oxysterols receptor LXR-alpha

1

13

High-throughput

0.494

High

1098303

TBX2
T-box transcription factor TBX2

1

2

High-throughput

0.494

High

1270373

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.494

High

1279160

RAI1
Retinoic acid-induced protein 1

1

11

High-throughput

0.494

High

1315023

ZZZ3
ZZ-type zinc finger-containing protein 3

1

3

High-throughput

0.494

High

1328743

KDM2B
Lysine-specific demethylase 2B

1

12

High-throughput

0.494

High

1328748

AP2B
Transcription factor AP-2-beta

1

2

High-throughput

0.494

High

1328751

SCMH1
Polycomb protein SCMH1

1

1

High-throughput

0.494

High

1328752

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

1

High-throughput

0.494

High

1328753

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

4

High-throughput

0.494

High

1328759

TRIM5
Tripartite motif-containing protein 5

1

4

High-throughput

0.494

High

1328764

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

1

High-throughput

0.494

High

1328767

AATF
Protein AATF

1

1

High-throughput

0.494

High

1328768

RERE
Arginine-glutamic acid dipeptide repeats protein

1

9

High-throughput

0.494

High

1328775

RUVB1
RuvB-like 1

1

4

High-throughput

0.494

High

1328779

ZN451
E3 SUMO-protein ligase ZNF451

1

1

High-throughput

0.494

High

1328781

NEMO
NF-kappa-B essential modulator

1

16

High-throughput

0.494

High

445665

KCRM
Creatine kinase M-type

1

1

High-throughput

0.489

High

539613

PYGM
Glycogen phosphorylase, muscle form

1

2

High-throughput

0.489

High

556865

MYH1
Myosin-1

1

11

High-throughput

0.489

High

556939

MYH7
Myosin-7

1

11

High-throughput

0.489

High

563023

MYH6
Myosin-6

1

11

High-throughput

0.489

High

563062

MYH8
Myosin-8

1

11

High-throughput

0.489

High

1061538

ACTN3
Alpha-actinin-3

1

3

High-throughput

0.489

High

1252024

TRI72
Tripartite motif-containing protein 72

1

4

High-throughput

0.489

High

1316744

WDFY3
WD repeat and FYVE domain-containing protein 3

1

4

High-throughput

0.489

High

1328750

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

5

High-throughput

0.489

High

1328770

MYH13
Myosin-13

1

11

High-throughput

0.489

High

1328780

MYH4
Myosin-4

1

11

High-throughput

0.489

High

637925

NF1
Neurofibromin

1

3

High-throughput

0.479

High

1242018

SCYL2
SCY1-like protein 2

1

6

Small-scale

0.479

High

1291066

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

6

Small-scale

0.479

High

180553

PLS1
Phospholipid scramblase 1

1

0

Small-scale

0.458

High

992257

SKP1
S-phase kinase-associated protein 1

1

4

High-throughput

0.445

High

131186

CLIC1
Chloride intracellular channel protein 1

1

1

Small-scale

0.437

High

528302

THIO
Thioredoxin

1

2

Small-scale

0.437

High

553235

KCRB
Creatine kinase B-type

1

1

Small-scale

0.437

High

684309

DDX6
Probable ATP-dependent RNA helicase DDX6

1

10

Small-scale

0.437

High

868735

LEG7
Galectin-7

1

1

High-throughput

0.437

High

870144

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

8

Small-scale

0.437

High

968379

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

7

Small-scale

0.437

High

1106612

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.437

High

1141217

BRD3
Bromodomain-containing protein 3

1

11

High-throughput

0.437

High

1158919

RBBP7
Histone-binding protein RBBP7

1

14

High-throughput

0.437

High

1161541

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.437

High

1328765

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

1

Small-scale

0.437

High

1328772

VPS4A
Vacuolar protein sorting-associated protein 4A

1

4

Small-scale

0.437

High

1328773

SHOC2
Leucine-rich repeat protein SHOC-2

1

5

Small-scale

0.437

High

511038

PNM6A
Paraneoplastic antigen-like protein 6A

1

1

High-throughput

0.407

High

1328755

AIFM3
Apoptosis-inducing factor 3

2

0

High-throughput

0.328

High

238778

SSX4
Protein SSX4

1

0

High-throughput

0.282

High

519527

MYBB
Myb-related protein B

1

0

High-throughput

0.282

High

621916

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.282

High

1308546

ZN584
Zinc finger protein 584

1

0

High-throughput

0.282

High

1311580

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.282

High

1328754

ZN714
Zinc finger protein 714

1

0

High-throughput

0.282

High

1328758

PAPOG
Poly(A) polymerase gamma

1

0

High-throughput

0.282

High

1328771

ZN490
Zinc finger protein 490

1

0

High-throughput

0.282

High

1328774

TCF19
Transcription factor 19

1

0

High-throughput

0.282

High

1328777

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.282

High

1328778

ZN175
Zinc finger protein 175

1

0

High-throughput

0.282

High

1273174

CHM1B
Charged multivesicular body protein 1b

1

0

Small-scale

0.249

Low

1328746

CTL1
Choline transporter-like protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025