HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	24945803, 31239290, 32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000794 - condensed nuclear chromosome GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1233
+	Hs
		259250 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SMC2_HUMAN (3-1214): 4.82e-78: 283: 18.14
+	Hs
		260514 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SMC4_HUMAN (4-1216): 4.66e-77: 281: 20.21
+	Hs
		260622 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SMC3_HUMAN (3-1229): 5.78e-69: 255: 15.78
+	Hs
		1130194 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SMC1A_HUMAN (1-1233): 1.05e-127: 425: 100.00
+	Hs
		1086761 BPTF_HUMAN (67-161): 9.91e-11: 68.9: 41.05		SMC1A_HUMAN (1-1233): 1.05e-127: 425: 100.00
+	Sp
		314037 YK82_SCHPO (49-215): 1.44e-35: 147: 26.35		SMC1_SCHPO (1-1225): 8.38e-75: 273: 32.93
+	Hs
		334106 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SMC2_HUMAN (3-1214): 4.82e-78: 283: 18.14
+	Hs
		1446396 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SMC4_HUMAN (4-1216): 4.66e-77: 281: 20.21
+	Hs
		1446446 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SMC3_HUMAN (3-1229): 5.78e-69: 255: 15.78
+	Hs
		1288014 PB1_HUMAN (15-951): 7.52e-20: 98.6: 11.32		SMC3_HUMAN (3-1229): 5.78e-69: 255: 15.78
+	Hs
		342097 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		MYH6_HUMAN (415-1138): 4.76e-27: 122: 9.38