HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: ATAD5 (Q96QE3)
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)
Gene: ATAD5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.943

Property	Details
Experiments	31753913, 32416067, 33961781, 30554943, 21555454, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Bromodomain
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1844
+	Hs
		1141272 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		674297 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		260085 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		NIPBL_HUMAN (66-837): 6.67e-54: 211: 12.10
+	Hs
		259533 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		RFC1_HUMAN (433-1276): 4.61e-53: 207: 14.77
+	Hs
		260212 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		CTF18_HUMAN (998-1222): 2.18e-34: 146: 17.57
+	Hs
		259949 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		259588 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		ATRX_HUMAN (88-1036): 2.63e-11: 71.5: 13.08
+	Hs
		1141173 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		NIPBL_HUMAN (66-837): 6.67e-54: 211: 12.10
+	Hs
		769999 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		RFC1_HUMAN (433-1276): 4.61e-53: 207: 14.77
+	Hs
		674093 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		RFC1_HUMAN (433-1276): 4.61e-53: 207: 14.77
+	Hs
		674271 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		TITIN_HUMAN (17-1124): 1.44e-33: 145: 8.28
+	Hs
		770059 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		RFC1_HUMAN (433-1276): 4.61e-53: 207: 14.77
+	Hs
		1129599 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		674162 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		1357894 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		CTF18_HUMAN (998-1222): 2.18e-34: 146: 17.57
+	Hs
		342153 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		MAP1A_HUMAN (6-1227): 4.23e-11: 70.7: 7.00
+	Dm
		119660 M9PB30_DROME (166-1043): 2.39e-09: 64.7: 9.22		M9PB30_DROME (11-756): 8.32e-30: 132: 6.94