HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 1025
+	Hs
		890712 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		161674 GAK_HUMAN (9-151): 1.05e-38: 141: 17.42		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		1153452 CC14A_HUMAN (5-169): 4.17e-36: 133: 23.78		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		260524 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		260572 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYH14_HUMAN (595-972): 3.69e-09: 63.1: 14.89
+	Hs
		725123 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		890672 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		161596 GAK_HUMAN (9-151): 1.05e-38: 141: 17.42		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		254484 CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29		ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81