Protein: ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1)

Gene: ATS4, ADAMTS4
Organism: Homo sapiens
Interactions: 61
UniProt ID: O75173

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0002020 - protease binding
GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257243

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

2

11

High-throughput

0.811

High

257242

LRP6
Low-density lipoprotein receptor-related protein 6

1

5

High-throughput

0.691

High

257296

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

13

High-throughput

0.691

High

257262

TRAF2
TNF receptor-associated factor 2

2

2

High-throughput

0.628

High

257264

BIRC2
Baculoviral IAP repeat-containing protein 2

2

3

High-throughput

0.628

High

257274

FRAS1
Extracellular matrix organizing protein FRAS1

2

20

High-throughput

0.628

High

257298

LOXL2
Lysyl oxidase homolog 2

2

4

High-throughput

0.628

High

257241

LRP5
Low-density lipoprotein receptor-related protein 5

1

5

High-throughput

0.618

High

129448

MANBA
Beta-mannosidase

2

1

High-throughput

0.574

High

175476

RA51B
DNA repair protein RAD51 homolog 2

2

1

High-throughput

0.574

High

257258

XIAP
E3 ubiquitin-protein ligase XIAP

2

4

High-throughput

0.574

High

257260

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

3

High-throughput

0.574

High

257265

TBB3
Tubulin beta-3 chain

2

4

High-throughput

0.574

High

257272

TBA1A
Tubulin alpha-1A chain

2

5

High-throughput

0.574

High

257280

K0232
Uncharacterized protein KIAA0232

2

1

High-throughput

0.574

High

257288

TBB1
Tubulin beta-1 chain

2

6

High-throughput

0.574

High

257291

BIRC6
Baculoviral IAP repeat-containing protein 6

2

2

High-throughput

0.574

High

257297

DICER
Endoribonuclease Dicer

2

1

High-throughput

0.574

High

257244

NOE2
Noelin-2

1

2

High-throughput

0.536

High

257248

TBB5
Tubulin beta chain

1

4

High-throughput

0.536

High

257250

BGLR
Beta-glucuronidase

1

1

High-throughput

0.536

High

257255

BMP8B
Bone morphogenetic protein 8B

1

5

High-throughput

0.536

High

257257

TBA4A
Tubulin alpha-4A chain

1

5

High-throughput

0.536

High

257263

OS9
Protein OS-9

1

1

High-throughput

0.536

High

257278

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

1

High-throughput

0.536

High

257252

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.513

High

257283

LGMN
Legumain

1

0

High-throughput

0.513

High

257286

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.513

High

257290

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.513

High

257245

A1AT
Alpha-1-antitrypsin

1

1

Small-scale

0.506

High

257256

TIMP3
Metalloproteinase inhibitor 3

1

3

Small-scale

0.501

High

206260

RA51C
DNA repair protein RAD51 homolog 3

1

1

High-throughput

0.489

High

257247

INSR
Insulin receptor

1

10

High-throughput

0.489

High

257249

IGF1R
Insulin-like growth factor 1 receptor

1

10

High-throughput

0.489

High

257251

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.489

High

257253

IDS
Iduronate 2-sulfatase

1

3

High-throughput

0.489

High

257254

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

1

High-throughput

0.489

High

257266

RCN2
Reticulocalbin-2

1

1

High-throughput

0.489

High

257268

TRBP2
RISC-loading complex subunit TARBP2

1

1

High-throughput

0.489

High

257269

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

1

High-throughput

0.489

High

257270

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

4

High-throughput

0.489

High

257275

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

4

High-throughput

0.489

High

257276

P3H3
Prolyl 3-hydroxylase 3

1

2

High-throughput

0.489

High

257279

HMGC2
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic

1

2

High-throughput

0.489

High

257281

SC65
Endoplasmic reticulum protein SC65

1

2

High-throughput

0.489

High

257284

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.489

High

257287

TOR3A
Torsin-3A

1

1

High-throughput

0.489

High

257293

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.489

High

257282

YTDC1
YTH domain-containing protein 1

1

1

High-throughput

0.481

High

257294

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

1

High-throughput

0.479

High

257261

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.460

High

257246

AACT
Alpha-1-antichymotrypsin

1

1

Small-scale

0.457

High

257259

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.328

High

257273

DPH6
Diphthine--ammonia ligase

2

0

High-throughput

0.328

High

257277

CCD33
Coiled-coil domain-containing protein 33

2

0

High-throughput

0.328

High

257285

ITPA
Inosine triphosphate pyrophosphatase

2

0

High-throughput

0.328

High

257292

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.328

High

257267

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.279

Low

257271

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.279

Low

257295

FEZ2
Fasciculation and elongation protein zeta-2

1

0

High-throughput

0.279

Low

257289

NSUN3
tRNA

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024