HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: CNNM3 (Q8NE01)
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)
Gene: CNNM3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	17353931, 24632616
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CBS~Y_phosphatase
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 707
+	Hs
		1242821 TP4A1_HUMAN (1-172): 1.27e-58: 182: 79.07		CNNM3_HUMAN (1-707): 0: 909: 100.00
+	Hs
		1021810 TP4A2_HUMAN (4-172): 8.42e-53: 167: 77.52		CNNM3_HUMAN (1-707): 0: 909: 100.00
+	Hs
		1144582 TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74		CNNM3_HUMAN (1-707): 0: 909: 100.00
+	Hs
		1274603 TP4A1_HUMAN (1-172): 1.27e-58: 182: 79.07		CNNM2_HUMAN (131-691): 0: 703: 48.32
+	Hs
		1159772 TP4A1_HUMAN (1-172): 1.27e-58: 182: 79.07		CNNM4_HUMAN (114-691): 0: 696: 47.91
+	Hs
		1021825 TP4A2_HUMAN (4-172): 8.42e-53: 167: 77.52		CNNM2_HUMAN (131-691): 0: 703: 48.32
+	Hs
		1021801 TP4A2_HUMAN (4-172): 8.42e-53: 167: 77.52		CNNM4_HUMAN (114-691): 0: 696: 47.91
+	Hs
		1274604 TP4A1_HUMAN (1-172): 1.27e-58: 182: 79.07		CNNM1_HUMAN (150-705): 0: 610: 47.11
+	Hs
		1021828 TP4A2_HUMAN (4-172): 8.42e-53: 167: 77.52		CNNM1_HUMAN (150-705): 0: 610: 47.11
+	Dm
		2649 PRL1_DROME (6-172): 1.24e-46: 152: 57.49		UEX_DROME (129-694): 0: 624: 37.29