HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27880917
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~Y_phosphatase
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 461
+	Hs
		655292 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		P85A_HUMAN (48-455): 9.1e-92: 295: 79.17
+	Hs
		129257 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		P85B_HUMAN (56-453): 2.19e-87: 283: 74.12
+	Hs
		782828 TENS1_HUMAN (3-168): 1.7e-45: 161: 16.39		CSK_HUMAN (357-456): 1.18e-19: 93: 34.65
+	Hs
		782797 TENS3_HUMAN (4-168): 1.59e-40: 147: 14.84		CSK_HUMAN (357-456): 1.18e-19: 93: 34.65
+	Hs
		433843 TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85		LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85
+	Hs
		523025 TENS3_HUMAN (4-168): 1.59e-40: 147: 14.84		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Rn
		222449 PTEN_RAT (5-163): 2.29e-41: 144: 18.86		SRC_RAT (323-459): 5.91e-19: 91.2: 24.14
+	Hs
		433303 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		YES_HUMAN (317-459): 6.84e-19: 91.2: 23.72
+	Hs
		782795 TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74		CSK_HUMAN (357-456): 1.18e-19: 93: 34.65
+	Rn
		222445 PTEN_RAT (5-163): 2.29e-41: 144: 18.86		CSK_RAT (286-457): 6.83e-19: 90.8: 24.86
+	Hs
		789107 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		FRK_HUMAN (256-459): 1.27e-18: 90: 24.04
+	Hs
		146680 TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74		SOCS7_HUMAN (36-171): 6.33e-16: 82.2: 27.74
+	Hs
		181830 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		SOCS1_HUMAN (46-169): 5.58e-13: 69.8: 23.20