Protein: INT11
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)

Gene: INT11, INTS11
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q5TA45

Gene Ontology (top 5):
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1215019

INT9
Integrator complex subunit 9

6

14

Small-scale

0.956

High

1215021

INT10
Integrator complex subunit 10

3

1

Small-scale

0.827

High

717845

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.811

High

1215003

INT4
Integrator complex subunit 4

2

3

Small-scale

0.776

High

1215020

INT13
Integrator complex subunit 13

2

3

Small-scale

0.767

High

994257

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

4

Small-scale

0.699

High

130497

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.691

High

722983

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.691

High

1150984

PCH2
Pachytene checkpoint protein 2 homolog

3

1

High-throughput

0.678

High

1215007

INT14
Integrator complex subunit 14

2

3

Small-scale

0.611

High

480177

RU1C
U1 small nuclear ribonucleoprotein C

2

1

High-throughput

0.606

High

1039756

CREB5
Cyclic AMP-responsive element-binding protein 5

2

2

High-throughput

0.606

High

1157449

PKN1
Serine/threonine-protein kinase N1

2

2

High-throughput

0.606

High

1214995

SPIC
Transcription factor Spi-C

2

1

High-throughput

0.606

High

1214999

TFG
Protein TFG

2

2

High-throughput

0.606

High

1215006

LENG8
Leukocyte receptor cluster member 8

2

3

High-throughput

0.606

High

1215017

TF7L2
Transcription factor 7-like 2

2

4

High-throughput

0.606

High

1215018

PLS4
Phospholipid scramblase 4

2

1

High-throughput

0.606

High

911266

IMA5
Importin subunit alpha-5

2

4

High-throughput

0.601

High

1214986

INT3
Integrator complex subunit 3

2

1

Small-scale

0.584

High

1215023

INT6
Integrator complex subunit 6

2

1

Small-scale

0.584

High

225023

TLX3
T-cell leukemia homeobox protein 3

2

0

High-throughput

0.580

High

277104

PROP1
Homeobox protein prophet of Pit-1

2

0

High-throughput

0.580

High

288433

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.580

High

330195

VENTX
Homeobox protein VENTX

2

0

High-throughput

0.580

High

351444

TBX6
T-box transcription factor TBX6

2

0

High-throughput

0.580

High

733159

OTX1
Homeobox protein OTX1

2

0

High-throughput

0.580

High

1065947

VAC14
Protein VAC14 homolog

2

0

High-throughput

0.580

High

1098561

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.580

High

1133099

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.580

High

1156018

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.580

High

1186946

KR151
Keratin-associated protein 15-1

2

0

High-throughput

0.580

High

1214989

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.580

High

1214997

F222B
Protein FAM222B

2

0

High-throughput

0.580

High

1215004

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.580

High

1215010

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

396289

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

954700

SEM1
26S proteasome complex subunit SEM1

2

1

Small-scale

0.571

High

1214996

OXER1
Oxoeicosanoid receptor 1

2

1

High-throughput

0.553

High

180534

PLS1
Phospholipid scramblase 1

1

1

High-throughput

0.541

High

1214991

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

Small-scale

0.537

High

347087

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

611900

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.536

High

621890

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

787750

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.536

High

872416

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.536

High

909035

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

923500

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

958964

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.536

High

977515

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

4

High-throughput

0.536

High

1065233

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1162971

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1215001

SOSB2
SOSS complex subunit B2

1

2

High-throughput

0.536

High

1215011

SOSB1
SOSS complex subunit B1

1

2

High-throughput

0.536

High

1215016

ENY2
Transcription and mRNA export factor ENY2

1

1

High-throughput

0.536

High

1215009

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

428161

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

1098711

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.513

High

1214990

RAD9B
Cell cycle checkpoint control protein RAD9B

1

0

High-throughput

0.513

High

1215013

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

920025

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.508

High

1215005

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1215008

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

405481

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

627978

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

995080

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

241939

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

345929

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

372253

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

400971

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

487408

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

667332

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

4

Small-scale

0.479

High

830889

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

904822

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

979797

H4
Histone H4

1

5

High-throughput

0.479

High

1099990

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

1113333

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1214988

INT5
Integrator complex subunit 5

1

3

High-throughput

0.479

High

1214993

INT1
Integrator complex subunit 1

1

3

High-throughput

0.479

High

1214998

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

342214

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

1215012

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.458

High

1215014

INT2
Integrator complex subunit 2

1

0

Small-scale

0.458

High

457489

TBB5
Tubulin beta chain

1

1

High-throughput

0.445

High

910934

IMA1
Importin subunit alpha-1

1

4

High-throughput

0.445

High

1215015

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.445

High

1214992

SEML
Putative protein SEM1, isoform 2

1

1

High-throughput

0.437

High

239090

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.426

High

506739

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1214987

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.316

High

1215002

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

1215024

HSF4
Heat shock factor protein 4

2

0

High-throughput

0.316

High

342584

LY86
Lymphocyte antigen 86

2

0

High-throughput

0.313

High

1215022

DSE
Dermatan-sulfate epimerase

1

0

High-throughput

0.282

High

1176987

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1215000

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

0

High-throughput

0.279

Low

1215026

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

959488

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

888461

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low

1214994

S22AO
Steroid transmembrane transporter SLC22A24

1

0

High-throughput

0.232

Low

1215025

PCDGG
Protocadherin gamma-B4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025