HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 726
+	Hs
		260758 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		1067170 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		631613 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		261039 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		555470 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		1067038 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		1349695 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		555299 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		631492 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		243698 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		260921 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		245038 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		555690 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		555430 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		998866 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		555569 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Hs
		555570 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50
+	Hs
		244634 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244848 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		555528 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68